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Viruses

  • 14-05-2025

    Joint open letter COGEM and ZKBS on the ERA of new vaccine developments based on samRNAs and VRPs

    In this Joint open letter to the European Commission, the Netherlands Commission on G...

    Policy reports
    CGM/250514-01 View more
  • 10-12-2024

    Risk Classification of Organisms: Pathogenicity classification of DNA and RNA viruses

    The Netherlands Commission on Genetic Modification (COGEM) advises the Dutch governme...

    Classification lists
    CGM/241210-02 View more
  • 10-07-2024

    Considering endogenous retroviruses present in mammalian species in environmental risk assessment

    COGEM had a literature study carried out to gain more insight in the possible environ...

    Research reports
    CGM 2024-03 View more
  • 17-06-2024

    Advice on the decision by the European Commission on the GMO status of viral replicon particles

    The European Commission (EC) has made a decision on the status of viral replicon part...

    Advisory letters
    CGM/240617-01 View more
  • 29-09-2023

    Risk Classification of Organisms: Pathogenicity classification of DNA and RNA viruses (Status September 2023)

    NOTE: This list has been updated in 2024 (see CGM/241210-02) The Netherlands Commissi...

    Classification lists
    CGM/230929-01 View more
  • 23-12-2022

    Generic downscaling of containment requirements for work with viral replicons derived from alphaviruses and flaviviruses

    Much research is being done on the development and application of ‘viral replicons’. ...

    Advisory reports
    CGM/221223-01 View more
  • 23-12-2022

    Viral replicon systems and their biosafety aspects –Inventory and description of viral replicon systems and characteristics relevant for risk assessment

    Much attention is being paid to the development and application of viral replicons, b...

    Research reports
    CGM 2022-06 View more
  • 17-11-2021

    Risk Classification of Organisms: Pathogenicity classification of RNA and DNA viruses. Status November 2021

    NOTE: This list has been updated in 2023 (see CGM/230929-01).   The Netherlands ...

    Classification lists
    CGM/211117-01 View more
  • 09-06-2021

    Review of containment levels for working with replication-deficient lentiviral and gamma­retro­viral vectors under contained use

    In 2009 COGEM issued generic advice on appropriate containment levels for laboratory ...

    Advisory reports
    CGM/210218-01 View more
  • 24-03-2021

    Generic environmental risk assessment of clinical trials with MVA vectors

    The modified vaccinia virus Ankara (MVA) is a biologically contained virus with a his...

    Advisory reports
    CGM/210324-01 View more
  • 24-03-2021

    Generic environmental risk assessment of replication-deficient adenoviral vectors in clinical trials

    Vectors derived from adenoviruses (adenoviral (AdV) vectors) are the most commonly us...

    Advisory reports
    210324-02 View more
  • 15-07-2019

    Characteristics and pathogenicity determination of insect-specific RNA and DNA viruses

    COGEM advices the Dutch Government on the required containment measures for activitie...

    Research reports
    CGM 2019-01 View more