Klinische studie Archives | COGEM

20-05-2025
Advice Reassessment of the threshold values for the presence of free lentiviral and retroviral vector particles in clinical trials with ex vivo transduced cells

In certain gene therapies, cells from the patient are genetically altered outside the...

Advisory reports
CGM/250520-01 View more
14-05-2025
Joint open letter COGEM and ZKBS on the ERA of new vaccine developments based on samRNAs and VRPs

In this Joint open letter to the European Commission, the Netherlands Commission on G...

Policy reports
CGM/250514-01 View more
07-05-2020
Generic environmental risk assessment of gene therapies that use GM cells containing free lentiviral particles

A generic environmental risk assessment has been prepared for gene therapy trials in ...

Advisory reports
CGM/200507-01 View more
11-02-2020
Generic environmental risk assessment of clinical trials with AAV vectors

Hundreds of clinical trials have been carried out worldwide in which use was made of ...

Advisory reports
CGM/190905-01 View more
04-09-2015
Research report Assessment of preclinical gene therapy studies worldwide

Frequently, the success of preclinical gene therapy studies in animal models is repor...

Research reports
CGM 2015-03 View more
12-01-2011
Replication-competent non-human viruses for use in clinical gene therapy: an inventory study

All living organisms are exposed to viruses. In general, viruses infect only a single...

Research reports
CGM 2010-10 View more