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Contained use

  • 19-08-2025

    Advice Explanation of the COGEM formula for calcu­lating free lentiviral or gammaretroviral vector particles after ex vivo transduction

    In biomedical or clinical research, cells are often genetically modified using lentiv...

    Advisory reports
    CGM/250819-01 View more
  • 20-05-2025

    Advice Reassessment of the threshold values for the presence of free lentiviral and retroviral vector particles in clinical trials with ex vivo transduced cells

    In certain gene therapies, cells from the patient are genetically altered outside the...

    Advisory reports
    CGM/250520-01 View more
  • 30-04-2025

    Advice on tightening conditions for generic downscaling of containment requirements for the use of transgenes in alphavirus replicons

    In 2022 COGEM advised that laboratory work with viral replicons derived from alphavir...

    Advisory reports
    CGM/250430-01 View more
  • 11-03-2025

    Advice on generic containment measures for activities involving arthropod biological control agents in PKb-I research greenhouses

    Biological control agents may be introduced into greenhouses and growth chambers wher...

    Advisory reports
    CGM/250311-02 View more
  • 10-12-2024

    Overview of micro-organisms other than viruses, bacteria, fungi or parasites, classified by COGEM

    The Netherlands Commission on Genetic Modification (COGEM) advises the Dutch governme...

    Classification lists
    CGM/241210-03 View more
  • 02-12-2024

    Overview of containment measures for genetically modified plants (Update December 2024)

    When activities are carried out with genetically modified (GM) plants under contained...

    Classification lists
    CGM/241202-01 View more
  • 15-11-2023

    Overview of micro-organisms other than viruses, bacteria, fungi or parasites, classified by COGEM

    NOTE: This list has been updated in 2024 (see CGM/241210-03) The Netherlands Commissi...

    Classification lists
    CGM/231115-01 View more
  • 29-09-2023

    Risk Classification of Organisms: Pathogenicity classification of DNA and RNA viruses (Status September 2023)

    NOTE: This list has been updated in 2024 (see CGM/241210-02) The Netherlands Commissi...

    Classification lists
    CGM/230929-01 View more
  • 09-12-2021

    Risk Classification of Organisms: Pathogenicity classification of parasites Status December 2021

    NOTE: This classification has been updated in 2024 (see CGM/241127-03) The Netherland...

    Classification lists
    CGM/211209-01 View more
  • 06-09-2016

    Pollen load on thrips and its natural ennemies

    Regulation for experiments with GM crops in contained facilities such as greenhouses ...

    Research reports
    CGM 2016-02 View more