The Netherlands Commission on Genetic Modification

COGEM advises the government on the risks of genetic modification for humans and the environment and identifies ethical and societal issues

News

Stay up to date with the latest news, current developments and upcoming events from COGEM.
24-11-2025

Welcome to our renewed website!

We are pleased to inform you that our website has been given a renewed layout and str...

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02-10-2025

Advice on the threshold value of free viral parti­cles in clinical studies available in English

COGEM has published an English translation of her advice on amending the threshold va...

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02-10-2025

Research report ‘Introgression from cultivated plants into their wild relatives’

The outcrossing of genetically modified (GM) plants to wild relatives (introgression)...

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02-10-2025

COGEM advice clarifying the proper use of the ‘COGEM formula’ is now available in English

COGEM has published an English translation of her advice on the explanation of the us...

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11-12-2024

Updated overview lists of risk group classifications

COGEM advises on the pathogenicity classes of (micro)organisms and viruses, or on the...

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18-10-2024

Access to gene therapy requires a different approach

A large number of new gene therapies will become available in the coming years. These...

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27-08-2024

Advances in the application of GM phages in research, development and industry

COGEM has commissioned research into the latest developments surrounding genetic modi...

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10-07-2024

Considering endogenous retroviruses present in mammalian species in environmental risk assessment

COGEM had a literature study carried out to gain more insight in the possible environ...

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25-06-2024

Marketing Patterns of Genetically Modified Food in Dutch Grocery Stores

The Russian invasion of Ukraine created severe uncertainties for global food markets....

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29-05-2024

Project call for a research project on unintended germline modification in new gene therapies

Address project bids to: F. van der Wilk, General Secretary COGEM; info@cogem.net The...

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Who is COGEM?

The Netherlands Commission on Genetic Modification (COGEM) is an independent scientific advisory body of the Dutch govern­ment with the statutory tasks of advising on the risks to humans and the environment posed by genetically modified organisms, and informing the government about ethical and societal aspects of genetic modification.

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COGEM

Publications

COGEM regularly publishes new advice, reports and other publications in English. Search our publications using the search bar below.

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Publications in preparation

Find out what advice and research projects COGEM is currently working on.

Documents in preparation

Highlighted publications

A selection of publications recently publisched by COGEM.

More publications
19-08-2025

Advice Explanation of the COGEM formula for calcu­lating free lentiviral or gammaretroviral vector particles after ex vivo transduction

In biomedical or clinical research, cells are often genetically modified using lentiv...

Advisory reports
CGM/250819-01 View more
19-09-2025

Introgression from cultivated plants into their wild relatives

The outcrossing of genetically modified (GM) plants to wild relatives, and the subseq...

Research reports
CGM 2025-02 View more
20-05-2025

Advice Reassessment of the threshold values for the presence of free lentiviral and retroviral vector particles in clinical trials with ex vivo transduced cells

In certain gene therapies, cells from the patient are genetically altered outside the...

Advisory reports
CGM/250520-01 View more
14-05-2025

Joint open letter COGEM and ZKBS on the ERA of new vaccine developments based on samRNAs and VRPs

In this Joint open letter to the European Commission, the Netherlands Commission on G...

Policy reports
CGM/250514-01 View more
05-12-2024

Risk Classification of Organisms: Pathogenicity classification of (a)patho­genic fungi Status November 2024

The Netherlands Commission on Genetic Modification (COGEM) advises the Dutch governme...

Classification lists
CGM/241205-01 View more
02-12-2024

Overview of containment measures for genetically modified plants (Update December 2024)

When activities are carried out with genetically modified (GM) plants under contained...

Classification lists
CGM/241202-01 View more
27-11-2024

Risk Classification of Organisms: Pathogenicity classification of (a)pathogenic bacteria (Update November 2024)

The Netherlands Commission on Genetic Modification (COGEM) advises the Dutch governme...

Classification lists
CGM/241127-02 View more
17-06-2024

Advice on the decision by the European Commission on the GMO status of viral replicon particles

The European Commission (EC) has made a decision on the status of viral replicon part...

Advisory letters
CGM/240617-01 View more

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